Ganoderma is used as a supplement in health promotion programs for a variety of ingredients (such as polysaccharides, triterpenoids, and proteins), because of their immunomodulation effects such as improving the immune system. Many diseases are caused by an imbalance of body functions and the accumulation of toxins in the body. Ganoderma may help the body to rid itself of toxins and strengthen the body's natural immune system. In addition to its use for hypertension, hepatoprotective activity, lowering blood sugar levels, the capacity for inhibition of platelet aggregation is also proven. Production of interleukin-2 (IL-2) and interferon (IFN) has significantly increased after treatment with Ganoderma. Cancer cells that have evolved through multiple genetic alterations lead to altered growth, differentiation and control of apoptosis. The aggressiveness of cancer is characterized by tumor invasion and metastasis. Studies in vitro have shown that Ganoderma is able to inhibit the growth of human bladder cancer and cell migration. Different mechanisms are responsible for it. Anti-cancer properties of Ganoderma can be attributed to the diversity of its chemical composition which may imply its use in the prevention of side effects of chemotherapy and radiotherapy.
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